Clinical and Epidemiological Characteristics of Scarlet Fever in Russia

Relevance. In recent decades, large outbreaks of scarlet fever have been reported in European and Asian countries. Severe forms the infection become more frequent number complications has also increased. Aim. To assess incidence Russian Federation using official statistical sources, to identify clinical features among adults. Materials methods. Analysis level dynamics long-term entire population different age groups Russia from 1890 2021 was performed based on data annual forms. A epidemiological descriptive retrospective census study conducted case histories patients diagnosed with “scarlet fever” The Infectious Disease Clinical Hospital No. 2 Moscow Healthcare Department 2010 2022. Results. Three major cycles (40-50 years) can be distinguished long term regard incidence. 1986, rise noted after 30 years since previous one it less intensive. first cycle, rates increased gradually over almost 10 beginning 1891. subsequent years, remained high (220-280 per 100,000), decreasing markedly 50-60 100,000 only by 1917-1918. second 1918 1942, characterized increasing (up 462 population). third cycle (1946 - 1981), rate reached a peak 1955 (531.8 population), started decrease afterwards. There were lasting 3–6 this period fourth (1982-1991) not so large. (2007–2021), decreased 7.3 times (from 45.4 6.2 100 thousand). average during 29.8 thousand. 2022, streptococcal 2.8 (including – 3 times). increases observed group 0-14 14 older 298,2 34,1 from1,6 0,1respectively). As (fourth cycle), children aged 3-6 main contributors (the 452,1 100,000). admitted hospital 24 (18–45 years). an increase 2017. During period, hospitalized adults half. most cases (98.56%) had moderate condition at admission severe (1.44%). common comorbid diagnoses ENT-organs infections (9%), urinary tract (3.35%) Wolf-Parkinson-White syndrome (2.87%). Scarlet complicated course 19 (9.09%). treatment used cephalosporin (52.63%) penicillin (41.63%). Conclusions. This demonstrated stable downward trend until 2021. (18.7 hospitalizations decreased. 5 carried out accordance recommendations antibiotic resistance pathogen.